Fans remember the calls against their team and are pretty quick to forget ones in their favor. There have absolutely been bad calls against us, but we've had plenty bounce our way.
The only one I'm still not happy about is the holding - we went like 2 full years without a holding call our way against a conference opponent and that's bizarre. I can see a chunk of it being reputation (you're really calling holding on Iowa/Wisconsin/Michigan? But they're so well coached!), and a chunk being we haven't had the guys rushing the passer who can make the OL grab. But I do think there's more there, probably just in the refs having too many things they're looking for. They have points of emphasis for every team/game, and if they're always being told to watch our DL for roughing the passer or what have you it takes focus away from potential holding.
I dunno, bit of a ramble there - TL;DR, something is up with the holding calls. I don't buy a general "refs have it out for us" narrative, but definitely agree they suck and have made bad calls.